A clinical research study for adults of African, Caribbean, or Central or South American descent.

This clinical research study is investigating if focal segmental glomerulosclerosis (FSGS) is genetic in some patients and is caused by a variation in the apolipoprotein L1 (APOL1) gene. If you are an adult of African, Caribbean, or Central or South American descent and have been diagnosed with FSGS, you may be able to take part.

Find a Participating Site

About the study.

Investigational genetic testing can be done to see if you were born with the variation in your APOL1 gene that can increase the risk and progression of FSGS. The study will require blood and saliva samples to determine if you have this gene variation. The results of this investigational genetic test may qualify you for a future clinical research study for adults with FSGS.

The test used to determine if you have an APOL1 gene variation is not approved by the Food and Drug Administration (FDA) in the United States or any health authorities in other countries. This means that it is not available outside a research study and is not intended to drive decisions about your medical care. If you would like more information about this investigational genetic test, please ask the study doctor.

We are currently enrolling adults 18 years and older who have been diagnosed with biopsy-confirmed FSGS to take part in this clinical research study. It may be appropriate for those who meet the following criteria:

Male or female of African, Caribbean, or Central or South American descent
Are 18 years of age or older
Diagnosed with FSGS via a previously done kidney biopsy
Willing and able to comply with the testing requirements

Those who qualify will receive this investigational genetic testing at no cost. If you qualify, you may be compensated for your study-related time and reimbursed for travel.

Find a participating site.

Enter your zip code below or click on the map to find the participating research site(s) nearest you.

Zip Code

e.g., 12345

View all participating sites

[{"SiteID":7704,"SiteName":"Cortes-Maisonet","LastName":"Cortes-Maisonet","FirstName":"Gregorio","ContactPerson":"TBD TBD","Institution":"GCM Medical Group, PSC","Address":"Urb. Floral Park 62 Calle Jose Marti, San Juan, Puerto Rico 00917","Address1":"Urb. Floral Park","Address2":"62 Calle Jose Marti","City":"San Juan","State":"Puerto Rico","ZipCode":"00917","ContactPhone":"TBD","ContactEmail":"TBD@gmail.com","ContactPreference":"Email","Latitude":18.421788,"Longitude":-66.054323,"EnableWeb":true,"FutureSite":false,"Country":"PR","CountryName":"Puerto Rico","International":true,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"San Juan, Puerto Rico"},{"SiteID":7207,"SiteName":"Rizk","LastName":"Rizk","FirstName":"Dana","ContactPerson":"Maria El Hachem","Institution":"University of Alabama at Birmingham (UAB) - The Kirklin Clinic (TKC)","Address":"2000 6th Avenue S, Birmingham, AL 35233","Address1":"2000 6th Avenue S","Address2":"","City":"Birmingham","State":"AL","ZipCode":"35233","ContactPhone":"205-975-0549","ContactEmail":"drizk@uab.edu","ContactPreference":"Email","Latitude":33.505474,"Longitude":-86.798062,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Birmingham, AL"},{"SiteID":6908,"SiteName":"Meyer","LastName":"Meyer","FirstName":"Jill","ContactPerson":"Maria Alvarez","Institution":"California Institute of Renal Research","Address":"340 Fourth Avenue, Chula Vista, CA 91910","Address1":"340 Fourth Avenue","Address2":"","City":"Chula Vista","State":"CA","ZipCode":"91910","ContactPhone":"619-422-2687 x8077","ContactEmail":"jmeyer@bnmg.org","ContactPreference":"Email","Latitude":32.638813,"Longitude":-117.084235,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Chula Vista, CA"},{"SiteID":7204,"SiteName":"Raj","LastName":"Raj","FirstName":"Dominic","ContactPerson":"Muhammed Siddiqi","Institution":"The George Washington University Medical Faculty Associates","Address":"2150 Pennsylvania Ave NE, Washington, DC 20037","Address1":"2150 Pennsylvania Ave NE","Address2":"","City":"Washington","State":"DC","ZipCode":"20037","ContactPhone":"202-741-2284","ContactEmail":"draj@mfa.gwu.edu","ContactPreference":"Email","Latitude":38.901208,"Longitude":-77.048515,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Washington, DC"},{"SiteID":7538,"SiteName":"Mere","LastName":"Mere","FirstName":"Constance","ContactPerson":"Debra Odor","Institution":"Howard University Hospital","Address":"2041 Georgia Avenue, NW, Washington, DC 20060","Address1":"2041 Georgia Avenue, NW","Address2":"","City":"Washington","State":"DC","ZipCode":"20060","ContactPhone":"202-865-625","ContactEmail":"cmere@howard.edu","ContactPreference":"Email","Latitude":38.917531,"Longitude":-77.020442,"EnableWeb":false,"FutureSite":true,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/future-marker.png","MarkerTitle":"Washington, DC"},{"SiteID":7539,"SiteName":"Greenbaum","LastName":"Greenbaum","FirstName":"Laurence","ContactPerson":"Mone Anzai","Institution":"Children\u0027s Healthcare of Atlanta - Center for Advanced Pediatrics","Address":"1400 Tullie Road NE, Atlanta, GA 30329","Address1":"1400 Tullie Road NE","Address2":"","City":"Atlanta","State":"GA","ZipCode":"30329","ContactPhone":"404-727-6994","ContactEmail":"lgreen6@emory.edu","ContactPreference":"Email","Latitude":33.831564,"Longitude":-84.332224,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Atlanta, GA"},{"SiteID":6912,"SiteName":"Luscy","LastName":"Luscy","FirstName":"C. Peter","ContactPerson":"Paige Menier","Institution":"Renal Associates of Baton Rouge","Address":"5131 O\u0027Donovan Drive, Baton Rouge, LA 70808","Address1":"5131 O\u0027Donovan Drive","Address2":"","City":"Baton Rouge","State":"LA","ZipCode":"70808","ContactPhone":"225-787-4893 x268","ContactEmail":"cpluscy@renalassociates.com","ContactPreference":"Email","Latitude":30.403953,"Longitude":-91.112146,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Baton Rouge, LA"},{"SiteID":7201,"SiteName":"Waikar","LastName":"Waikar","FirstName":"Sushrut","ContactPerson":"Mia Colona","Institution":"Boston Medical Center","Address":"1 Boston Medical Center Plaza, Boston, MA 02118","Address1":"1 Boston Medical Center Plaza","Address2":"","City":"Boston","State":"MA","ZipCode":"02118","ContactPhone":"(617)638-7332","ContactEmail":"swaikar@bu.edu","ContactPreference":"Email","Latitude":42.336017,"Longitude":-71.069519,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Boston, MA"},{"SiteID":7205,"SiteName":"Denker","LastName":"Denker","FirstName":"Bradley","ContactPerson":"Wilanda Gabrial","Institution":"Beth Israel Deaconess Medical Center (BIDMC)","Address":"330 Brookline Avenue, Boston, MA 02215","Address1":"330 Brookline Avenue","Address2":"","City":"Boston","State":"MA","ZipCode":"02215","ContactPhone":"617-975-7637","ContactEmail":"bdenker@bidmc.harvard.edu","ContactPreference":"Email","Latitude":42.345370,"Longitude":-71.100629,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Boston, MA"},{"SiteID":6965,"SiteName":"Germain","LastName":"Germain","FirstName":"Michael","ContactPerson":"Joy Whitbeck","Institution":"Renal and Transplant Associates of New England, PC","Address":"100 Wason Avenue, Springfield, MA 01107","Address1":"100 Wason Avenue","Address2":"","City":"Springfield","State":"MA","ZipCode":"01107","ContactPhone":"413-512-1110","ContactEmail":"michael.germain@baystatehealth.org","ContactPreference":"Email","Latitude":42.125152,"Longitude":-72.613634,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Springfield, MA"},{"SiteID":6906,"SiteName":"Aqeel","LastName":"Aqeel","FirstName":"Ahmed","ContactPerson":"Joseph Yarbrough","Institution":"Paragon Health PC","Address":"521 E Michigan Avenue, Kalamazoo, MI 49007","Address1":"521 E Michigan Avenue","Address2":"","City":"Kalamazoo","State":"MI","ZipCode":"49007","ContactPhone":"269-384-6180 x231","ContactEmail":"aaqeel@nephrologycenter.com","ContactPreference":"Email","Latitude":42.294203,"Longitude":-85.577089,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Kalamazoo, MI"},{"SiteID":6909,"SiteName":"Polack","LastName":"Polack","FirstName":"Donovan","ContactPerson":"Pamela Pettiford","Institution":"St. Louis Kidney Care","Address":"11155 Dunn Road Building 1, St. Louis, MO 63136","Address1":"11155 Dunn Road","Address2":"Building 1","City":"St. Louis","State":"MO","ZipCode":"63136","ContactPhone":"314-739-4691","ContactEmail":"donovanp@sbcglobal.net","ContactPreference":"Email","Latitude":38.776589,"Longitude":-90.240251,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"St. Louis, MO"},{"SiteID":6907,"SiteName":"Wooldridge","LastName":"Wooldridge","FirstName":"Thomas","ContactPerson":"Dianna Christian","Institution":"Nephrology and Hypertension Associates, Ltd.","Address":"1542 Medical Park Circle, Tupelo, MS 38801","Address1":"1542 Medical Park Circle","Address2":"","City":"Tupelo","State":"MS","ZipCode":"38801","ContactPhone":"662-397-3609","ContactEmail":"lrayburn@nephrologyms.com","ContactPreference":"Email","Latitude":34.235380,"Longitude":-88.715937,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Tupelo, MS"},{"SiteID":6913,"SiteName":"Kathresal","LastName":"Kathresal","FirstName":"Amarnath","ContactPerson":"Sherice Dove","Institution":"Durham Nephrology Associates","Address":"4419 Ben Franklin Boulevard, Durham, NC 27704","Address1":"4419 Ben Franklin Boulevard","Address2":"","City":"Durham","State":"NC","ZipCode":"27704","ContactPhone":"919-477-3005 x232","ContactEmail":"akathresal@durneph.com","ContactPreference":"Email","Latitude":36.048072,"Longitude":-78.890674,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Durham, NC"},{"SiteID":7202,"SiteName":"Olabisi","LastName":"Olabisi","FirstName":"Opeyemi","ContactPerson":"Robin Gilliam","Institution":"Duke University Medical Center","Address":"2424 Erwin Road, Durham, NC 27710","Address1":"2424 Erwin Road","Address2":"","City":"Durham","State":"NC","ZipCode":"27710","ContactPhone":"919-681-9008","ContactEmail":"opeyemi.olabisi@duke.edu","ContactPreference":"Email","Latitude":36.009299,"Longitude":-78.941729,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Durham, NC"},{"SiteID":6910,"SiteName":"Ryu","LastName":"Ryu","FirstName":"Jeffrey","ContactPerson":"Sandra Konery","Institution":"Nevada Kidney Disease and  Hypertension Centers","Address":"1581 Mount Mariah Drive, Las Vegas, NV 89106","Address1":"1581 Mount Mariah Drive","Address2":"","City":"Las Vegas","State":"NV","ZipCode":"89106","ContactPhone":"702-239-5906","ContactEmail":"jryu@nkdhc.com","ContactPreference":"Email","Latitude":36.205402,"Longitude":-115.256994,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Las Vegas, NV"},{"SiteID":6894,"SiteName":"Fox","LastName":"Fox","FirstName":"Chester","ContactPerson":"Ashleigh Skipper","Institution":"Urban Family Practice","Address":"564 Niagara St., Buffalo, NY 14201","Address1":"564 Niagara St.","Address2":"","City":"Buffalo","State":"NY","ZipCode":"14201","ContactPhone":"716-919-1130","ContactEmail":"cfox@circuitclinical.com","ContactPreference":"Email","Latitude":42.898761,"Longitude":-78.890232,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Buffalo, NY"},{"SiteID":7203,"SiteName":"Moritz","LastName":"Moritz","FirstName":"Michael","ContactPerson":"Matthew Butoryak","Institution":"Children\u0027s Hospital of Pittsburgh of UPMC","Address":"4401 Penn Avenue AOB 2nd Floor, Pittsburgh, PA 15224","Address1":"4401 Penn Avenue","Address2":"AOB 2nd Floor","City":"Pittsburgh","State":"PA","ZipCode":"15224","ContactPhone":"412-692-7060","ContactEmail":"moritzml@upmc.edu","ContactPreference":"Email","Latitude":40.467566,"Longitude":-79.953107,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Pittsburgh, PA"},{"SiteID":7206,"SiteName":"Pisoni","LastName":"Pisoni","FirstName":"Roberto","ContactPerson":"Linda Walker","Institution":"Medical University of South Carolina (MUSC)","Address":"96 Jonathan Lucas Street, Charleston, SC 29425","Address1":"96 Jonathan Lucas Street","Address2":"","City":"Charleston","State":"SC","ZipCode":"29425","ContactPhone":"843-792-8166","ContactEmail":"pisoni@musc.edu","ContactPreference":"Email","Latitude":32.812867,"Longitude":-80.046376,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Charleston, SC"},{"SiteID":6914,"SiteName":"Moustafa","LastName":"Moustafa","FirstName":"Moustafa","ContactPerson":"Mohangi Patel","Institution":"South Carolina Nephrology and Hypertension, Inc.","Address":"3709 Magnolia Street, Orangeburg, SC 29118","Address1":"3709 Magnolia Street","Address2":"","City":"Orangeburg","State":"SC","ZipCode":"29118","ContactPhone":"803-531-2220","ContactEmail":"mmoustafa@scnephrology.net","ContactPreference":"Email","Latitude":33.530385,"Longitude":-80.838341,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Orangeburg, SC"},{"SiteID":6903,"SiteName":"Mandayam","LastName":"Mandayam","FirstName":"Sreedhar","ContactPerson":"Bhavin Shah","Institution":"Prolato Clinical Research Center PCRC","Address":"8990 Kirby Dr., Houston, TX 77054","Address1":"8990 Kirby Dr.","Address2":"","City":"Houston","State":"TX","ZipCode":"77054","ContactPhone":"832-338-9118","ContactEmail":"smandayam@prolatoresearch.com","ContactPreference":"Email","Latitude":29.673852,"Longitude":-95.412733,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Houston, TX"}]

Active site locations

About FSGS.

FSGS is a disease that scars the kidney, often leading to kidney failure. FSGS can have many different causes, including infection, disease, some medications, and genetics. If you are of African, Caribbean, or Central or South American descent, it is possible that your condition is genetic and caused by a variation in the apolipoprotein L1 (APOL1) gene. APOL1 is believed to contribute to FSGS disease progression.

What you should know about clinical research studies.

What is a clinical research study?

Clinical research studies, also called clinical trials, are carefully designed research studies conducted in people to determine if an investigational medicine is safe and effective. We encourage interested individuals to speak first with their doctor about their eligibility to enroll in a clinical research study. New medicines are made possible by the volunteers who participate in clinical research studies.

In most countries, the regulatory health authority, such as the FDA in the United States, requires that several phases of clinical research be performed to determine the safety and effectiveness of investigational drugs and certain investigational medical devices.

Clinical research studies must be approved by an institutional review board (IRB) or ethics committee (EC). An IRB/EC is a group that is responsible for helping to protect the rights and welfare of study participants.

How long will study participation last?

Participation in this study consists of one visit for the blood and saliva sample collection. The investigational genetic test may qualify you for a future clinical research study for adults with FSGS.

Thank you for your consideration of this important study.