A clinical research study for adults of African or Caribbean descent.

This clinical research study is investigating if focal segmental glomerulosclerosis (FSGS) is genetic in some patients and is caused by a variation in the apolipoprotein L1 (APOL1) gene. If you have been diagnosed with FSGS, you may be able to take part.

Find a Participating Site

About the study.

Genetic testing can be done to see if you were born with the variation in your APOL1 gene that causes genetic FSGS. The study will require a blood test to determine if you have this gene variation. The results of this genetic test may qualify you for a future clinical research study for adults with FSGS.

The test used to determine if you have an APOL1 gene variation is not FDA approved, which means that it is not available outside of a research study and is not intended to drive decisions about your medical care. The FDA and other regulatory agencies have approved this test for research purposes ONLY. As with any genetic test, there is a risk of inaccurate results. Vertex is taking efforts to reduce this risk by testing your blood sample under industry standard processes and guidelines. If you would like more information about this genetic test, please ask your study doctor.

We are currently enrolling adults 18 years or older who have been diagnosed with biopsy-confirmed FSGS to take part in this clinical research study. It may be appropriate for those who meet the following criteria:

Male or female of African or Caribbean descent
Diagnosed with FSGS via a kidney biopsy
Willing and able to comply with the testing requirements

Those who qualify will receive this testing at no cost. If you qualify, you may be compensated for your study-related time and travel. You may also be eligible for travel assistance.

Find a participating site.

Enter your zip code below or click on the map to find the participating research site(s) nearest you.

View all participating sites

[{"SiteID":6908,"SiteName":"Meyer","LastName":"Meyer","FirstName":"Jill","ContactPerson":"Maria Alvarez","Institution":"California Institute of Renal Research","Address":"340 Fourth Ave., Chula Vista, CA 91910","Address1":"340 Fourth Ave.","Address2":"","City":"Chula Vista","State":"CA","ZipCode":"91910","ContactPhone":"619-422-2687 x8077","ContactEmail":"malvarez@balboaunited.org","ContactPreference":"Email","Latitude":32.638813,"Longitude":-117.084235,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Chula Vista, CA"},{"SiteID":7032,"SiteName":"Kusnir","LastName":"Kusnir","FirstName":"Jorge","ContactPerson":"Sonya Robinson","Institution":"Florida Premier Research Institute, LLC","Address":"1788 West Fairbanks Ave., Winter Park, FL 32789","Address1":"1788 West Fairbanks Ave.","Address2":"","City":"Winter Park","State":"FL","ZipCode":"32789","ContactPhone":"407-925-6772","ContactEmail":"srobinson@fpcresearch.com","ContactPreference":"Email","Latitude":28.592847,"Longitude":-81.373066,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Winter Park, FL"},{"SiteID":6912,"SiteName":"Luscy","LastName":"Luscy","FirstName":"C. Peter","ContactPerson":"Paige Menier","Institution":"Renal Associates of Baton Rouge","Address":"5131 O\u0027Donovan Dr., Baton Rouge, LA 70808","Address1":"5131 O\u0027Donovan Dr.","Address2":"","City":"Baton Rouge","State":"LA","ZipCode":"70808","ContactPhone":"225-787-4893 x268","ContactEmail":"paige.menier@frenovarenalresearch.com","ContactPreference":"Email","Latitude":30.403953,"Longitude":-91.112146,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Baton Rouge, LA"},{"SiteID":6965,"SiteName":"Germain","LastName":"Germain","FirstName":"Michael","ContactPerson":"Joy Whitbeck","Institution":"Renal and Transplant Associates of New England, PC","Address":"100 Wason Ave., Springfield, MA 01107","Address1":"100 Wason Ave.","Address2":"","City":"Springfield","State":"MA","ZipCode":"01107","ContactPhone":"413-512-1110","ContactEmail":"jwhitbeck@rtane.org","ContactPreference":"Email","Latitude":42.125152,"Longitude":-72.613634,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Springfield, MA"},{"SiteID":6906,"SiteName":"Aqeel","LastName":"Aqeel","FirstName":"Ahmed","ContactPerson":"Joseph Yarbrough","Institution":"Paragon Health PC","Address":"521 E Michigan Ave., Kalamazoo, MI 49007","Address1":"521 E Michigan Ave.","Address2":"","City":"Kalamazoo","State":"MI","ZipCode":"49007","ContactPhone":"269-384-6180 x231","ContactEmail":"joseph.yarbrough@frenovarenalresearch.com","ContactPreference":"Email","Latitude":42.294203,"Longitude":-85.577089,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Kalamazoo, MI"},{"SiteID":6909,"SiteName":"Polack","LastName":"Polack","FirstName":"Donovan","ContactPerson":"Pamela Pettiford","Institution":"Polack Renal LLC","Address":"11155 Dunn Rd. N Bldg 1, St. Louis, MO 63136","Address1":"11155 Dunn Rd.","Address2":"N Bldg 1","City":"St. Louis","State":"MO","ZipCode":"63136","ContactPhone":"314-739-4691","ContactEmail":"pamela.pettiford@frenovarenalresearch.com","ContactPreference":"Email","Latitude":38.776589,"Longitude":-90.240251,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"St. Louis, MO"},{"SiteID":6907,"SiteName":"Wooldridge","LastName":"Wooldridge","FirstName":"Thomas","ContactPerson":"Dianna Christian","Institution":"Nephrology and Hypertension Associates, LTD","Address":"1542 Medical Park Circle, Tupelo, MS 38801","Address1":"1542 Medical Park Circle","Address2":"","City":"Tupelo","State":"MS","ZipCode":"38801","ContactPhone":"662-397-3609","ContactEmail":"dianna.christian@frenovarenalresearch.com","ContactPreference":"Email","Latitude":34.235380,"Longitude":-88.715937,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Tupelo, MS"},{"SiteID":6891,"SiteName":"Aiello","LastName":"Aiello","FirstName":"Joseph","ContactPerson":"Stephanie Evans","Institution":"Mountain Kidney \u0026 Hypertension Associates (MKHA), PA","Address":"10 McDowell St., Asheville, NC 28801","Address1":"10 McDowell St.","Address2":"","City":"Asheville","State":"NC","ZipCode":"28801","ContactPhone":"828-258-8545","ContactEmail":"stephaniee@mtnkidney.com","ContactPreference":"Email","Latitude":35.583210,"Longitude":-82.554132,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Asheville, NC"},{"SiteID":6905,"SiteName":"Kennelly","LastName":"Kennelly","FirstName":"Christina","ContactPerson":"Kelly Woodell","Institution":"Tryon Medical Partners","Address":"6060 Piedmont Row Dr. S, Charlotte, NC 28210","Address1":"6060 Piedmont Row Dr. S","Address2":"","City":"Charlotte","State":"NC","ZipCode":"28210","ContactPhone":"704-586-9386","ContactEmail":"kwoodell@javararesearch.com","ContactPreference":"Email","Latitude":35.148355,"Longitude":-80.840647,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Charlotte, NC"},{"SiteID":6913,"SiteName":"Kathresal","LastName":"Kathresal","FirstName":"Amarnath","ContactPerson":"Sherice Dove","Institution":"Durham Nephrology Associates","Address":"4419 Ben Franklin Blvd., Durham, NC 27704","Address1":"4419 Ben Franklin Blvd.","Address2":"","City":"Durham","State":"NC","ZipCode":"27704","ContactPhone":"919-477-3005 x232","ContactEmail":"sdove@durneph.com","ContactPreference":"Email","Latitude":36.048072,"Longitude":-78.890674,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Durham, NC"},{"SiteID":6915,"SiteName":"Zenenberg","LastName":"Zenenberg","FirstName":"Robert","ContactPerson":"Courtney Maricic","Institution":"Nephrological Associates","Address":"83 Hanover Rd., Florham Park, NJ 07932","Address1":"83 Hanover Rd.","Address2":"","City":"Florham Park","State":"NJ","ZipCode":"07932","ContactPhone":"973-736-2212","ContactEmail":"cmaricic@newjerseykidney.com","ContactPreference":"Email","Latitude":40.796208,"Longitude":-74.376067,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Florham Park, NJ"},{"SiteID":6910,"SiteName":"Ryu","LastName":"Ryu","FirstName":"Jeffrey","ContactPerson":"Sandra Konery","Institution":"Nevada Kidney Disease \u0026 Hypertension Center - Northwest","Address":"2450 Fire Mesa St., Las Vegas, NV 89128","Address1":"2450 Fire Mesa St.","Address2":"","City":"Las Vegas","State":"NV","ZipCode":"89128","ContactPhone":"702-239-5906","ContactEmail":"sandra.konery@frenovarenalresearch.com","ContactPreference":"Email","Latitude":36.205402,"Longitude":-115.256994,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Las Vegas, NV"},{"SiteID":6894,"SiteName":"Fox","LastName":"Fox","FirstName":"Chester","ContactPerson":"Ashleigh Skipper","Institution":"Urban Family Practice","Address":"564 Niagara St., Buffalo, NY 14201","Address1":"564 Niagara St.","Address2":"","City":"Buffalo","State":"NY","ZipCode":"14201","ContactPhone":"716-919-1130","ContactEmail":"askipper@circuitclinical.com","ContactPreference":"Email","Latitude":42.898761,"Longitude":-78.890232,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Buffalo, NY"},{"SiteID":6904,"SiteName":"Wenker","LastName":"Wenker","FirstName":"Matt","ContactPerson":"Zach Eardley","Institution":"New Horizons Clinical Research","Address":"9395 Kenwood Rd., Cincinnati, OH 45242","Address1":"9395 Kenwood Rd.","Address2":"","City":"Cincinnati","State":"OH","ZipCode":"45242","ContactPhone":"513-769-2770","ContactEmail":"zeardley@velocityclinical.com","ContactPreference":"Email","Latitude":39.226382,"Longitude":-84.380026,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Cincinnati, OH"},{"SiteID":6914,"SiteName":"Moustafa","LastName":"Moustafa","FirstName":"Moustafa","ContactPerson":"Mohangi Patel","Institution":"South Carolina Nephrology and Hypertension Center","Address":"3709 Magnolia St., Orangeburg, SC 29118","Address1":"3709 Magnolia St.","Address2":"","City":"Orangeburg","State":"SC","ZipCode":"29118","ContactPhone":"803-531-2220","ContactEmail":"mpatel@scnephrology.net","ContactPreference":"Email","Latitude":33.530385,"Longitude":-80.838341,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Orangeburg, SC"},{"SiteID":6903,"SiteName":"Mandayam","LastName":"Mandayam","FirstName":"Sreedhar","ContactPerson":"Bhavin Shah","Institution":"Prolato Clinical Research Center PCRC","Address":"8990 Kirby Dr., Houston, TX 77054","Address1":"8990 Kirby Dr.","Address2":"","City":"Houston","State":"TX","ZipCode":"77054","ContactPhone":"832-338-9118","ContactEmail":"bshah@prolatoresearch.com","ContactPreference":"Email","Latitude":29.673852,"Longitude":-95.412733,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Houston, TX"},{"SiteID":6911,"SiteName":"Patel","LastName":"Patel","FirstName":"Rakesh","ContactPerson":"Amy Reyna","Institution":"Privia Medical Group","Address":"9539 Huffmeister Rd., Houston, TX 77095","Address1":"9539 Huffmeister Rd.","Address2":"","City":"Houston","State":"TX","ZipCode":"77095","ContactPhone":"346-237-4868","ContactEmail":"areyna@javararesearch.com","ContactPreference":"Email","Latitude":29.916866,"Longitude":-95.630572,"EnableWeb":true,"FutureSite":false,"Country":"US","CountryName":"United States of America","International":false,"Deleted":false,"MarkerImageDefault":"images/active-marker.png","MarkerTitle":"Houston, TX"}]

Active site locations Potential site locations

About FSGS.

FSGS is a disease that scars the kidney, often leading to kidney failure. FSGS can have many different causes, including infection, disease, some medications, and genetics. If you are of African or Caribbean descent, it is possible that your condition is genetic and caused by a variation in the apolipoprotein L1 (APOL1) gene, which resides on chromosome 22. APOL1 has also been shown to contribute to FSGS disease progression.

What you should know about clinical research studies.

What is a clinical research study?

Clinical research studies, also called clinical trials, are carefully designed research studies in people to determine if an investigational medicine is safe and effective. We encourage patients to speak first with their doctor about their eligibility to enroll in a clinical research study. New medicines are made possible by the volunteers who participate in clinical research studies.

In most countries, the regulatory health authority, such as the Food and Drug Administration (FDA) in the United States, requires that several phases of clinical research be performed to better understand the safety and effectiveness of new investigational drugs and certain medical devices.

Clinical research studies must be approved by an institutional review board (IRB) or ethics committee (EC). An IRB/EC is a group that is responsible for helping to protect the rights and welfare of study participants.

How long will study participation last?

Participation in this study consists of one visit for the blood test. This test may qualify you for a future clinical research study for adults with FSGS.

Thank you for your consideration of this important study.